Global Human Microbiome Industry is Heading Towards MASSIVE Technological Reform

The study involved two major activities in estimating the Current and Expected Market Size of the Global Human Microbiome Market in the future. Exhaustive research was conducted to collect information on the market as well as its peer and parent markets. The next step was to validate these findings, assumptions, and sizing with industry experts across the value chain through primary research. Both top-down and bottom-up approaches were employed to estimate the complete market size. After that, market breakdown and data triangulation were used to estimate the market size of segments and sub-segments.

Recent Developments:

# In 2019, Seres collaborated with AstraZeneca to get a better understanding of the microbiome in augmenting the efficacy of cancer immunotherapy, including potential synergy with AstraZeneca compounds.

# In 2018, Enterome entered into a co-development and co-promotion agreement with Takeda for its investigational drug candidate EB8018. This drug is used in patients with Crohn's disease and has the potential to expand its use to other gastrointestinal (GI) disorders and liver diseases.

# In 2016, 4D Pharma acquired the production assets of Instituto Biomar to expand its clinical and production capabilities of live biotherapeutics.

Key questions addressed by the report:

# Who are the major market players in the human microbiome market?

# What are the regional growth trends and the largest revenue-generating regions for the market?

# What are the major drivers and challenges in the market?

# What are the major product segments in the market?

# What are the major technologies used in the human microbiome research spending market?

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Industry’s Revenue Growth Expectations:

The global human microbiome industry is expected to grow from USD 942 million in 2024 to USD 1,731 million by 2027, at a CAGR of 22.5 % during the forecast period.

Factors Influencing Global Industry Growth:-

Microbiomes are responsible for a wide variety of metabolic and developmental processes—from food digestion to vitamin synthesis and even brain function. They also play a major role in human conditions, such as obesity and inflammatory bowel disease.

Market growth is largely driven by the increasing focus on the development of human microbiome therapy. It has also become a validated target for drug development. The growing number of collaborations between market players is expected to offer a wide range of growth opportunities for market players during the forecast period.

Restraints:

# Lack of Expertise and Detailed Research

# Barriers in Proving the Causal Link Between Dysbiosis and Disease

Challenges:

# Government Regulations

Geographical Growth Scenario:

Europe to account for the largest share of the human microbiome market in 2022

Geographically, the global human microbiome market is segmented into four major geographies— North America, Europe, the Asia Pacific, and the Rest of the World (RoW). Europe is expected to account for the largest share of the global human microbiome market in 2022. The large share of this regional segment is mainly due to the high research activity in this region.

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Leading Market Players:

# Enterome Bioscience (France)

# E.I. du Pont de Nemours and Company (DuPont) (US)

# 4D Pharma (UK)

# Seres Therapeutics (US) and many more…

Various growth strategies have been adopted by these players, such as product launches, agreements, and acquisitions to increase their presence in the global human microbiome market.

Fill Finish Manufacturing - Emerging Trends | Global Future Forecasts | Major Industry Leaders

Fill-finish manufacturing is the process of aseptically filling biologics in any form such as solution, powder, or suspension in containers such as vials, syringes, cartridges, ampoules, bottles, and bags. It is an integral part of biopharmaceutical manufacturing after upstream-cell culture & downstream-separation and purification operations.

Key steps involved in the fill-finish process include:

# cleaning

# Sterilization

# filling

# stoppering

# Lyophilization

# capping

# crimping

# Visual inspection.

Factors Influencing Global Industry Growth:-

Technological advancements in fill-finish products, growth of the biopharmaceutical industry, rising adoption of prefilled syringes, and increase in fill-finish outsourcing are the major factors driving this market.

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Restraints:

# High Costs Associated With Isolators/Rabs

Opportunity:

# Growth of Biomanufacturing in Emerging Markets

Challenge:

# Challenges Associated With Manufacturing Prefilled Syringes

Industry’s Revenue Growth Expectations:

The global fill-finish manufacturing market is estimated to account for USD 2.96 Billion in 2017 and projected to reach USD 4.47 Billion by 2022, at a CAGR of 8.6%.

Geographical Growth Scenario:

In 2017, Europe is expected to account for the largest share of the global fill-finish manufacturing market. The large share of the European region is mainly attributed to factors such as the emergence of biosimilar market due to patent expiry of key biologic products, rising incidence of chronic disorders, and increasing focus of major players on enhancing their presence in Europe.

The APAC region is expected to grow at the highest CAGR over the next five years. The growth of the fill-finish manufacturing market in this region is fueled by the overall growth in the biopharmaceutical industry.

Target Audience:

# Biopharmaceutical companies

# Fill-finish product manufacturers

# Contract manufacturing companies

# Clinical research organizations

# NGOs and government organizations associated with fill-finish manufacturing

# Market research and consulting firms

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Leading Market Players:

# Becton, Dickinson and Company (US)

# West Pharmaceutical Services, Inc. (West Pharmaceutical Services) (US)

# Gerresheimer AG (Gerresheimer) (Germany)

# Robert Bosch GmbH (Robert Bosch) (Germany)

# IMA (Italy)

# OPTIMA (Germany) and many more…

Product launches remain at the center of the strategic growth initiatives adopted by a majority of key players in the global fill-finish manufacturing market.

These companies have been focusing on product launches to enhance their market presence. Players also focused on increasing their presence in high-growth markets through inorganic growth strategies, such as partnerships, collaborations, agreements, expansions, and acquisitions.

Sample Preparation Market - Major Factors of the Global Industry Growth

The sample preparation market comprises products used to prepare biological as well as chemical samples for the analysis of raw materials or final products primarily to determine the presence of unwanted materials. Sample preparation instruments, workstations, and consumables serve the purpose of the production of a homogeneous sub-sample, representative of the material submitted to a laboratory.

Objectives of the Study:

# To define and measure the Global Sample Preparation Industry with respect to products, applications, end users and regions

# To provide detailed information regarding major factors influencing growth of the market (drivers, restraints, opportunities, and industry-specific challenges)

# To strategically analyze micromarkets with respect to individual growth trends, future prospects, and contributions to the overall market

# To analyze opportunities in the market for stakeholders and provide details of the competitive landscape for market leaders

# To forecast the size of the market with respect to four main regions, namely, North America, Europe, Asia-Pacific, and the Rest of the World

# To strategically analyze the market structure and profile the key players of the global market and comprehensively analyze their core competencies

# To track and analyze competitive developments such as product deployments, agreements, collaborations, and partnerships; new product launches, product enhancements; expansions; acquisitions; and others (such as investments, and marketing and promotions) in the sample preparation market

Factors Influencing Global Industry Growth:-

A number of factors such as the shift from manual to automated sample preparation, increasing research in the field of genomics, increase in laboratory and R&D spending, global alliances among leading research institutes to boost drug discovery, increasing need for food analysis due to safety concerns, and rising adoption of modern extraction techniques are expected to drive the growth of the sample preparation market during the forecast period.

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Restraints:

# High Costs of Workstations Restrict Purchase

# Difficulty in Developing ‘One-Size-Fit-All’ Sample Preparation Kits

Opportunities:

# Growing Proteomics Market

# Personalized Medicine to Fuel the Demand for Sample Preparation Solutions

# Increased Government Investment in Medical Researches Set to Increase Market Applications

Industry’s Revenue Growth Expectations:

This report studies the sample preparation market for the forecast period of 2016 to 2021. This market is expected to reach USD 7,203.2 Million by 2021 from USD 5,512.2 Million in 2016, growing at a CAGR of 5.5%.

Geographical Growth Scenario:

Geographically, the global sample preparation market is divided into North America, Europe, Asia-Pacific, and the Rest of the World (Latin America, Middle East, and Africa). North America is expected to account for the largest share of the sample preparation market in 2016, followed by Europe, Asia-Pacific, and the Rest of the World. The Asia-Pacific market is projected to grow at the highest CAGR, and serves as a revenue pocket for companies offering sample preparation products.

Target Audience:

# Sample preparation instruments, consumables, accessories, and related products manufacturing companies

# Suppliers and distributors of sample preparation instruments, consumables, and accessories

# Research institutes and academic centers

# Pharmaceutical and biopharmaceutical companies

# Biotechnology companies

# Molecular diagnostic companies

# Food and beverage analysis companies

# Business research and consulting service providers

# Environmental testing organizations

# Government departments and agencies

# Venture capitalists

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Leading Market Players:

# Agilent Technologies, Inc. (U.S.)

# Danaher Corporation (U.S.)

# Illumina, Inc. (U.S.)

# QIAGEN N.V. (Netherlands)

# PerkinElmer, Inc. (U.S.) and many more…

The other players in this market have implemented various strategies to expand their global footprint and increase their market share. Major growth strategies followed by market players include new product launches, agreements, collaborations, and partnerships.

New product launches accounted for major share followed by agreements, collaborations, and partnerships which accounted for the second-largest share of the total number of key growth strategies adopted by players in the sample preparation market during 2013 to 2016. Acquisitions, product enhancement, and other developments (market promotions and grants) are some of the other strategies adopted by players to achieve growth in the sample preparation market.

Prominent Growth to be Observed in Global Protein Binding Assays Market due to Technological Makeover

Major Objectives of this Study:

# To define, describe, and forecast the Global Protein Binding Assay Industry on the basis of technology, end user, and regions.

# To provide detailed information about factors influencing market growth (drivers, restraints, opportunities, and industry-specific challenges).

# To strategically analyze the micromarkets with respect to individual growth trends, prospects, and contributions to the overall market.

# To analyze market opportunities for stakeholders and provide details of the competitive landscape for key players.

# To forecast the size of the market segments with respect to four major regional segments, namely, North America, Europe, Asia Pacific, and the Rest of the World (RoW).

# To profile the key players in the market and comprehensively analyze their market positions and core competencies.

# To track and analyze competitive developments such as partnerships, agreements, and joint ventures; mergers and acquisitions; product development; and research and development activities in the protein binding assay market

Factors Influencing Global Industry Growth:-

The increasing use of protein binding assays in pre-clinical research for studying the distribution properties of the drug, and the growing number of drug discovery activities, the minimizing drug discovery and development costs, and the increase in pharmaceutical R&D expenditure is driving the growth of this market.

Restraints:

# Issues with Existing Technologies

Opportunities:

# Growing CRO Industry

Challenges:

# Development of in Silico-Based Prediction Models

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Industry’s Revenue Growth Expectations:

The global protein binding assays market is projected to reach USD 425.7 million in 2023 from USD 256.1 million in 2018, at CAGR of 10.7%.

Geographical Growth Scenario:

Asia Pacific is expected to grow at the highest CAGR during the forecast period

The APAC market is projected to register the highest growth rate during the forecast period primarily due to factors such as, growth of clinical trial activities in several APAC countries. As a result of this, the pharmaceutical and biopharmaceutical companies are outsourcing their drug discovery and development activities to APAC-based CROs. This is one of the major factors driving the growth of the protein binding assay market in the Asia Pacific.

Target Audience:

# Government and academic institutes

# Protein binding assay providers

# R&D departments

# Contract research organizations

# Pharmaceutical & biotechnology companies

# Consulting firms

# Government associations

Leading Market Players:

# HTDialysis (US)

# Thermo Fisher Scientific (US)

# Merck (Germany)

# Sovicell (Germany) and many more…

Most companies focus on agreements, collaborations, and partnerships to compete in the market. The players also focus on increasing their presence in high-growth markets through acquisitions and product launches. 

Thermo Fisher (US), Sovicell (Germany) and 3B Pharmaceutical focus on partnerships, collaboration and license agreements to strengthen their position in the market.

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In 2017, Thermo Fisher was the leading player in the protein binding assay market. The company has a strong geographic presence across the US, Europe, Greater China, and Asia Pacific. The company focuses on a wide range of products offering in the protein binding assay market.

The company’s products are based on the equilibrium dialysis technology, which helps it dominate this market. The company focuses on partnerships to enhance its presence in the market. In 2018, Thermo Fisher partnered with The Montreal Neurological Institute (The Neuro) of the McGill University (Canada) to provide reagents and tools to understand neurological diseases.

Rising Focus on Preventive Medical Equipment Maintenance - A Major Milestone for the European Healthcare Industry

Key questions addressed in this Study:

# To define, describe, and forecast the European Medical Equipment Maintenance Industry by device, service, service provider, contract type, end user, and country.

# To provide detailed information regarding the major factors influencing the growth of the market (drivers, restraints, opportunities, and industry-specific challenges).

# To strategically analyze micromarkets with respect to individual growth trends, prospects, and contributions to the market.

# To analyze the opportunities in the market for stakeholders and provide details of the competitive landscape for market leaders.

# To forecast the size of the market segments with respect to European countries, namely, Germany, Italy, U.K., France, Spain, and Rest of Europe (RoE).

# To profile key players and comprehensively analyze their product portfolios, market positions, and core competencies.

# To track and analyze competitive developments such as agreements, partnerships, collaborations, mergers & acquisitions, and expansions in the European medical equipment maintenance market.

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Factors Influencing Global Industry Growth:-

The growth of the market is attributed to rising focus on preventive maintenance. Preventive maintenance is gaining prominence as planned inspections and medical device maintenance help avoid adverse incidents and medical-device related accidents.

Regular maintenance services provided by OEMs, ISOs, or in-house service technicians ensure safe, efficient, and long-lasting use of medical devices. The growing focus on implementing preventive maintenance strategies among healthcare organizations is expected to offer growth opportunities for service providers in the coming years.

Market Opportunities:

# Innovation in Service Offerings & Use of IoT

# Emergence of ISOS

Challenge:

                        # Survival of Players in a Highly Fragmented and 
                           Competitive Market

Upcoming Industry Trends:

# Market Consolidation

# Preference for Multi-Vendor Contracts

# Equipment Maintenance Insurance Tools for Imaging Centers

Industry’s Revenue Growth Expectations:

The European medical equipment maintenance market is expected to reach USD 8.93 billion by 2022 from USD 6.64 billion in 2017, at a CAGR of 6.1% during the forecast period.

Geographical Growth Scenario:

By region, the European medical equipment maintenance market is segmented into Germany, Italy, UK, France, Spain, and RoE. In 2017, Germany accounted for the largest share of the market; this regional segment is also expected to grow at highest CAGR during the forecast period, followed by Italy.

The high growth of the German market is attributed to the factors such as the significant presence of OEMs, growing medical technology market, well-established healthcare infrastructure and large installation base of medical equipment. Italy is the second largest growing market, factors such as focus on value-based healthcare system, and strategic expansion of market players, are expected to fuel the market growth in this country.

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Leading Market Players:

# GE Healthcare (U.S.)

# Koninklijke Philips N.V. (Netherlands)

# Siemens Healthineers (Germany)

# Toshiba Medical Systems Europe (Germany)

# Drägerwerk AG & Co. KGaA (Germany)

# TBS Group S.p.A. (Italy) and many more…

Partnerships, collaborations and agreements were the key growth strategies adopted by the market players to maintain and improve their position in the European medical equipment maintenance market. Mergers & acquisitions accounted for the second largest share of the overall growth strategy mapped from 2014-2017. Some of the leading players who adopted this strategy include Hitachi, Ltd. (Japan), Medtronic plc (Ireland), and Pantheon Healthcare Group (Italy).

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Bowel Management Systems - Expected Industrial Growth in Near Future

Objectives of the Study:

# To define, describe, and forecast the Global Bowel Management Systems Industry on the basis of product, patient type, end user, and region

# To provide detailed information regarding the major factors influencing global market growth (drivers, restraints, opportunities, and industry-specific challenges)

# To strategically analyze the micromarkets1 with respect to individual growth trends, future prospects, and contributions to the overall market

# To analyze the opportunities in the global market for stakeholders and provide details of the competitive landscape for global leaders

# To forecast the revenue of the market segments with respect to four main regions, namely, North America (US and Canada), Europe (Germany, France, UK, and Rest of Europe), Asia Pacific (India, China, Japan, and Rest of Asia Pacific), and the Rest of the World (Latin America, and Middle East & Africa)

# To strategically profile the key players and comprehensively analyze their global market ranking and core competencies

# To track and analyze competitive developments such as new product launches, agreements, mergers & acquisitions, and research and development activities in the global bowel management systems market

Research Period Considered for this Study:

Base Year: 2017

Forecasted Year: 2018

Forecast Period: 2018–2023

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Factors Influencing Global Industry Growth:-

Growth in the bowel management systems market is mainly driven by factors such as the expanding target patient and growing geriatric population, availability of technologically advanced bowel management products, and favorable reimbursement scenario in developed countries.

Major Market Growth Restraints:

# Discomfort Associated With the Use of Bowel Management Devices

# Patient Preference for Non-Invasive Clinical Management of Fi

Market Challenges:

# Underreporting of Fi

# Disparities in Reimbursement for Bowel Management Products in Emerging Countries

Industry’s Revenue Growth Expectations:

The global bowel management systems market is projected to reach USD 2.07 billion by 2023 from USD 1.74 billion in 2018, at a CAGR of 3.5% during the forecast period.

Geographical Growth Scenario:

The report covers the bowel management systems market across four major geographies, namely, North America, Europe, Asia Pacific, and the Rest of the World (RoW). Europe is expected to command the largest share of the market in 2018. The strong market position of Europe in the bowel management systems market is mainly due to the significant colorectal/bladder cancer & IBD disease burden, favorable reimbursement scenario, and the increase in its geriatric population.

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Leading Market Players:

The major players of the market include Coloplast (Denmark), Medtronic (Ireland), 3M (US), B. Braun (Germany), C.R. Bard (US), ConvaTec (UK), Consure Medical (India), Cogentix Medical (US), Aquaflush Medical Limited (UK), Axonics Modulation Technologies (US), ConvaTec (UK), Hollister (US), MBH-International A/S (Denmark), Mederi Therapeutics Inc. (US), Welland Medical limited (UK), and Wellspect HealthCare (Sweden).

An analysis of market developments between 2015 and 2018 revealed that growth strategies such as product launches and approvals, agreements, expansions, and acquisitions were adopted by market players to strengthen their product portfolios and maintain a competitive position in the bowel management systems market. Among these, product launches and approvals were the most widely adopted growth strategies

Stakeholders in the Global Industry:

# Bowel management product manufacturers

# Ostomy care bag manufacturers

# Third-party product suppliers and distributors

# Retail pharmacies and other off-the-shelf sales channels

# Raw material suppliers

# Market research and consulting firms

# National & international regulatory bodies

# Venture capitalist firms

# Hospitals & other healthcare providers